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    <article id="post-狗日的中年" class="article article-type-post" itemscope itemprop="blogPost">
  
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              <p>第一次进入社会工作，我19岁，在一个机械厂做体力活，每天像毛驴一样重复着围磨般的工作，那时候纠结我的最大人生困惑就是吃炒饭省钱还是吃炒面省钱。我的房东是个40岁左右的男人，每天四平八稳的睡到自然醒来，踱着方步把我们几个出租房检查一遍，接着就在大把富足的时间里打盹，喝茶，看天。更要命的，这狗日的居然早点就吃炖肉，香味像狗舌头一样撩涮着我的味觉。那时候，做梦都在盼望着我的40岁什么能到来，我也可以这样踱着方步在时光里浸润，那是一个多么向往年龄啊。
          
      
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    <article id="post-机器学习之分类器性能指标值ROC曲线、AUC值" class="article article-type-post" itemscope itemprop="blogPost">
  
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      <a href="/2016/10/28/机器学习之分类器性能指标值ROC曲线、AUC值/" class="article-date">
      <time datetime="2016-10-28T13:10:42.000Z" itemprop="datePublished">2016-10-28</time>
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              <h1 id="一-roc曲线"><a href="#一-roc曲线" class="headerlink" title="一 roc曲线"></a>一 roc曲线</h1><p>1、roc曲线：接收者操作特征(receiveroperating characteristic),roc曲线上每个点反映着对同一信号刺激的感受性。</p>
<p><strong>横轴</strong>：负正类率(false postive rate FPR)特异度，划分实例中所有负例占所有负例的比例；(1-Specificity)</p>
<p><strong>纵轴</strong>：真正类率(true postive rate TPR)灵敏度，Sensitivity(正类覆盖率)
          
      
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    <article id="post-《定风波·三月七日》" class="article article-type-post" itemscope itemprop="blogPost">
  
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      <a href="/2016/10/26/《定风波·三月七日》/" class="article-date">
      <time datetime="2016-10-26T14:34:51.000Z" itemprop="datePublished">2016-10-26</time>
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        <h2 id="定风波·三月七日"><a href="#定风波·三月七日" class="headerlink" title="定风波·三月七日"></a>定风波·三月七日</h2><hr>
<p>作者：苏轼</p>
<blockquote>
<p>三月七日，沙湖道中遇雨。<br>雨具先去，同行皆狼狈，余独不觉，已而遂晴，故作此词。</p>
</blockquote>
<pre><code>莫听穿林打叶声，何妨吟啸且徐行。
竹杖芒鞋轻胜马，谁怕？一蓑烟雨任平生。
料峭春风吹酒醒，微冷，山头斜照却相迎。
回首向来萧瑟处，归去，也无风雨也无晴。
</code></pre>
      
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    <article id="post-20种氨基酸的疏水性" class="article article-type-post" itemscope itemprop="blogPost">
  
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      <time datetime="2016-10-26T13:56:09.000Z" itemprop="datePublished">2016-10-26</time>
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              <p>20种氨基酸的疏水性见下面： （高正值的氨基酸具有更大的疏水性，而低负值的氨基酸则更加亲水）：
          
      
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    <article id="post-TRIzol-RNA提取方法" class="article article-type-post" itemscope itemprop="blogPost">
  
    <div class="article-meta">
      <a href="/2016/10/20/TRIzol-RNA提取方法/" class="article-date">
      <time datetime="2016-10-20T14:31:19.000Z" itemprop="datePublished">2016-10-20</time>
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              <h1 id="一、RNA的提取"><a href="#一、RNA的提取" class="headerlink" title="一、RNA的提取"></a><strong>一、RNA的提取</strong></h1><p><strong>（一）试剂准备</strong></p>
<p>1．TRIzol试剂。<br>2．氯仿<br>3．异丙醇<br>4．75%乙醇（DEPC H2O配制）<br>5．DEPC H2O<br>
          
      
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    <article id="post-药物化学训练问题重重" class="article article-type-post" itemscope itemprop="blogPost">
  
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      <a href="/2016/10/20/药物化学训练问题重重/" class="article-date">
      <time datetime="2016-10-20T09:37:28.000Z" itemprop="datePublished">2016-10-20</time>
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              <p>萨斯大学的Michael F. Rafferty教授近日在J. Med. Chem.杂志上发表文章“No Denying It: Medicinal Chemistry Training Is in Big Trouble”，谈论了自己对当下药物化学训练的一些观点看法（DOI: 10.1021/acs.jmedchem.6b00741）。<strong><a href="http://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.6b00741">文献链接</a></strong>
          
      
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    <article id="post-中药学数据库" class="article article-type-post" itemscope itemprop="blogPost">
  
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      <a href="/2016/05/22/中药学数据库/" class="article-date">
      <time datetime="2016-05-22T13:30:11.000Z" itemprop="datePublished">2016-05-22</time>
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              <h1 id="TCM-Database-Taiwan"><a href="#TCM-Database-Taiwan" class="headerlink" title="TCM Database @ Taiwan"></a>TCM Database @ Taiwan</h1><ul>
<li><strong>Introduction</strong></li>
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<p>Traditional Chinese Medicine Database@Taiwan is currently the most comprehensive and largest non-commercial TCM database available for download.
          
      
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    <article id="post-R绘图基础之高级绘图函数" class="article article-type-post" itemscope itemprop="blogPost">
  
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              <p>高级绘图命令：在图形设备上产生一个新的图区，它可能包括坐标轴，标签，标题等等。
          
      
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              <p>在R中，高级图形函数可以迅速简便地绘制不同类型的常见图形，但某些情况下，我们希望绘制些特殊要求的图形。比如在在已有的图中增加一组数据，加入注释，对特定的数据点添加标签等。
          
      
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        <p>[1]安装包：<br>install.packages()  #不加如何参数执行后，将显示镜像站点的列表，选择其中某个站点后，将看到该站点所有可用包的列表，选择其中一个包即可下载安装。</p>
<p>[2]如果知道自己所需要的包，直接将该软件包的名称作为参数提供给这个函数进行下载安装。<br>例如：install.packages(“maps”)<br>输入命令后选择下载的镜像站点，然后R将会自动下载安装。</p>
<p>[3]一般情况下，包可能会被作者更新，如果要更新所心在的包。使用命令：<br>update.packages()</p>
<p>[4]如果想要查看安装包的说明,使用installed.packages()命令，这将列出安装的包，以及它们的版本号、依赖关系等信息。</p>

      
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